A synthetic riboswitch with chemical band-pass response.
نویسندگان
چکیده
We designed a synthetic riboswitch containing an OFF and an ON riboswitch units fused in tandem. The resulting complex riboswitch functions as a chemical band-pass filter circuit.
منابع مشابه
Bacterial riboswitches
This wikipedia entry provides an extensive description of natural and engineered riboswitches. Most known riboswitches have been found in bacteria. This webpage provides a link to an electronic thesis file describing a riboswitch that responds to the herbicide atrazine. This web article discusses synthetic riboswitches. These are tools that researchers can use to control bacterial metabolism. T...
متن کاملMicrostrip Low-pass Filter with Sharp Roll off and Wide Stop-band Using Multiple Cascaded Modified Radial Stubs Resonators
This paper presents a novel microstrip low-pass filter with good performance. A complete detailed theoretical analysis for the proposed filter is given using equivalent circuit models. The proposed filter applying multiple cascaded modified radial stubs resonators provides a sharp cut off frequency response that has a 185 dB/GHz roll off rate. Also, U-shaped attenuators provide a wide stop-band...
متن کاملDevelopment of a 2,4-dinitrotoluene-responsive synthetic riboswitch in E. coli cells.
Riboswitches are RNA sequences that regulate expression of associated downstream genes in response to the presence or absence of specific small molecules. A novel riboswitch that activates protein translation in E. coli cells in response to 2,4-dinitrotoluene (DNT) has been engineered. A plasmid library was constructed by incorporation of 30 degenerate bases between a previously described trini...
متن کاملReprogramming Bacteria to Seek and Destroy a Herbicide
A major goal of synthetic biology is to reprogram cells to perform complex tasks. Here we show how a combination of in vitro and in vivo selection rapidly identifies a synthetic riboswitch that activates protein translation in response to the herbicide atrazine. We further demonstrate that this riboswitch can reprogram bacteria to migrate in the presence of atrazine. Finally, we show that incor...
متن کاملAn Efficient Algorithm to Design Nearly Perfect-Reconstruction Two-Channel Quadrature Mirror Filter Banks
In this paper, a novel technique for the design of two-channel Quadrature Mirror Filter (QMF) banks with linear phase in frequency domain is presented. To satisfy the exact reconstruction condition of the filter bank, low-pass prototype filter response in pass-band, transition band and stop band is optimized using unconstrained indirect update optimization method. The objective function is form...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 46 36 شماره
صفحات -
تاریخ انتشار 2010